Abnormalities of B cell subsets in patients with systemic lupus erythematosus
✍ Scribed by Thomas Dörner; Annett M. Jacobi; Jisoo Lee; Peter E. Lipsky
- Book ID
- 113717843
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 578 KB
- Volume
- 363
- Category
- Article
- ISSN
- 0022-1759
No coin nor oath required. For personal study only.
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## Abstract ## Objective B lymphocyte depletion has recently emerged as a promising approach to the treatment of systemic lupus erythematosus (SLE). As part of a phase I/II dose‐ranging trial of rituximab in the treatment of SLE, we evaluated the fate of discrete B cell subsets in the setting of s
## Abstract Echocardiographic examinations of 21 unselected patients with systemic lupus erythematosus revealed a wide variety of abnormalities. The abnormalities consisted of substantial pericardial effusion in five patients (24%) and a thickened pericardium in six patients (29%);significantly lar