Transcription factor Sp1 dysregulation i
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Bruce A. Citron; John S. Dennis; Ross S. Zeitlin; Valentina Echeverria
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Article
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2008
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John Wiley and Sons
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English
β 155 KB
π 1 views
## Abstract Altered gene expression occurs in central nervous system disorders, including Alzheimer's disease (AD). Transcription factor Sp1 may be involved insofar as it can regulate the expression of several ADβrelated proteins, including amyloid precursor protein (APP) and tau. Sp1 could itself