I n two previous papers the decline of the respiratory power of bovine articular cartilage ('41 a ) and the structure of the dehydrogenatic component of the respiratory system ('42) have been described. I n the present communication data are presented concerning the dehydrogenatic activity of bovine
Abnormal softening in articular cartilage. Its relationship to the collagen framework
β Scribed by Neil D. Broom
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 860 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Abnormal softening in articular cartilage is related to the presence of collagen fibers strongly aligned in a radial direction. In this paper, a morphologic model is proposed that provides a mechanism by which these radial arrays can develop passively from the more random, 3βdimensional network of fibers observed in normal articular cartilage.
π SIMILAR VOLUMES
The phenomenon of "growing old" is the summation of the degenerative changes which occur in all tissues. Some tissues undergo demonstrable degeneration at earlier ages than others. The degenerative changes are grossly apparent in some tissues and afford a definite index of the structural age of the
Collagen type I and type II were purified from equine flexor tendon and articular cartilage, respectively. Equal amounts of these collagens were cleaved with cyanogen bromide, and 11 mixtures containing increasing proportions of type II collagen were separated in seven identical sodium dodecyl sulfa
## Objective: To determine the sites of cleavage and denaturation of type ii collagen (cii) by collagenase(s) in healthy and osteoarthritic (oa) human articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 (mmp-1) and mmp-13. ## Methods: Single (per subject)