Abnormal sex cord formation and an intratesticular adrenal cortical nodule in a human fetus
✍ Scribed by Roosen-Runge, Edward C. ;Lund, Joanna
- Book ID
- 102743927
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 751 KB
- Volume
- 173
- Category
- Article
- ISSN
- 0003-276X
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✦ Synopsis
Abstract
A combination of two developmental abnormalities never described before, a nodule of adrenal cortical tissue and some severely stunted sex cords, in the right testis of a four‐month‐old human fetus are described in detail. In the left testis a few abnormal cords were found but no adrenal tissue was seen. The possible origin of the abnormalities is discussed. It is suggested on circumstantial evidence that the ectopic adrenal cortex migrated into the testis near the end of the period during which the pattern of sex cords becomes established (around day 40 ?) and began exerting an inhibiting influence on the development of the sex cords as soon as endocrine function began, probably somewhat before the end of the third month. This influence probably did not last long.