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Abnormal rapid Ca2+ release from sarcoplasmic reticulum of malignant hyperthermia susceptible pigs

✍ Scribed by Lucie Carrier; Michel Villaz; Yves Dupont


Book ID
115729824
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
463 KB
Volume
1064
Category
Article
ISSN
0005-2736

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Malignant hyperthermia: Effects of sarco
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In porcine malignant hyperthermia-susceptible (MHS) skeletal muscles, calcium release is abnormal and resting calcium may be elevated. Thus MHS muscles may have prolonged twitch relaxation and lower fusion frequencies, which would be augmented by inhibition of sarcoplasmic reticulum (SR) Ca2+ adenos