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Abnormal phenotype of cultured fibroblasts in human skin with chronic radiotherapy damage

✍ Scribed by Sylvie Delanian; Michèle Martin; Anne Bravard; Catherine Luccioni; Jean-Louis Lefaix


Book ID
119521938
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
242 KB
Volume
47
Category
Article
ISSN
0167-8140

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## Abstract A metallothionein‐like protein (MTP) is synthesized in normal diploid human skin fibroblasts cultured in Zn‐ or Cu‐supplemented medium. Synthesis of MTP is not detected in cells cultured without metal supplementation of complete tissue‐culture medium. Cultured fibroblasts from patients