Alzheimer's disease-associated presenili
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Janetta G. Culvenor; Fran Maher; Geneviève Evin; Fiorella Malchiodi-Albedi; Robe
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Article
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1997
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John Wiley and Sons
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English
β 395 KB
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The recently identified Alzheimer's disease-associated presenilin 1 and 2 (PS1 and PS2) genes encode two homologous multi membrane-spanning proteins. Rabbit antibodies to the N-terminal domain of PS1 detected PS1 in human neuroblastoma SH-SY5Y wild type and PS1 transfectants (SY5Y-PS1) as well as in