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Abnormal number of centrosomes and development of aneuploidy and nuclear pleomorphism in breast tumor cells

✍ Scribed by Y. Gusev; J. Sample; W.C. Dooley


Book ID
114136667
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
119 KB
Volume
98
Category
Article
ISSN
0165-4608

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We describe the application of lamin immunocytochemistry (ICC) and single-or double-target fluorescence in situ hybridization (FISH) on 4 pm thick frozen tissue sections as a method to facilitate scoring of aberrant chromosome copy numbers in colonic tumors. Analysis of FISH signals in colon tissue