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Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia

✍ Scribed by Tucholski, Janusz; Simmons, Micah S.; Pinner, Anita L.; Haroutunian, Vahram; McCullumsmith, Robert E.; Meador-Woodruff, James H.


Book ID
120241593
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
557 KB
Volume
146
Category
Article
ISSN
0920-9964

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## Abstract The N‐methyl‐D‐aspartate receptor (NMDAR) is fundamental to normal and pathological functioning of neurons. The receptor subunits are N‐glycosylated proteins synthesized in the endoplasmic reticulum (ER) that fold, mature, and oligomerize as they transit through the secretory pathway. A