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Abnormal homocysteine metabolism and glutathione depletion in yolk sacs and embryos of diabetic rats

โœ Scribed by S James; YingKing Wu; Stepan Melnyk; Patrycja Krakowiak; Mario Cleves; E Reece


Book ID
113426722
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
76 KB
Volume
189
Category
Article
ISSN
1097-6868

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Effects of depletion of reduced glutathione (GSH) on selenium (Se) embryotoxicity in cultured rat embryos were examined. Rat embryos at day 9.5 of gestation were cultured for 48 h in the presence of Se as either sodium selenite at 10 and 20 ยตM or sodium selenate at 30 and 100 ยตM. Embryonic GSH was d