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Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice

✍ Scribed by Hsieh, M-C; Yang, S-C; Tseng, H-L; Hwang, L-L; Chen, C-T; Shieh, K-R


Book ID
109866486
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
483 KB
Volume
34
Category
Article
ISSN
1476-5497

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## Abstract **Scope**: This study investigated the global transcriptional and metabolic changes occurring at multiple time points over 24 wk in response to a high‐fat diet (HFD). **Methods and results**: C57BL/6J mice were fed a HFD or normal diet (ND) over 24 wk. HFD‐fed mice developed early clin