Bronchioloalveolar carcinoma (BAC) is a particular type of adenocarcinoma of the lung which accounts for up to 9 per cent of pulmonary malignancies. The aetiology and pathogenesis of this unique neoplastic disease are still unclear. Three histological subtypes of BAC have been recognized: mucinous,
Abnormal Expression of the Retinoblastoma Gene in Ovarian Neoplasms and Correlation to P53 and K-ras Mutations
β Scribed by Robert R. Taylor; R.Ilona Linnoila; Joseph Gerardts; Michael G. Teneriello; John D. Nash; Robert C. Park; Michael J. Birrer
- Book ID
- 115616630
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 507 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0090-8258
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## Abstract Gene mutations in __APC__, __Kβras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __Kβras__ and __p53__ mutations rarely coβexist in the same tumor, indicating that these alterations do not represent a synergistic e