Abnormal basement membrane type IV collagen α-chain composition in labial salivary glands in Sjögren's syndrome

Overexpression of phosphorylated STAT-1α

Overexpression of phosphorylated STAT-1α in the labial salivary glands of patients with Sjögren's syndrome

✍ Ei Wakamatsu; Isao Matsumoto; Takanori Yasukochi; Yusuke Naito; Daisuke Goto; Mi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

## Abstract ## Objective To clarify the molecular mechanisms of Sjögren's syndrome (SS), we analyzed the functional role of the STAT‐1 gene, one of the interferon‐γ (IFNγ)–inducible genes, in labial salivary glands (LSGs) from SS patients. ## Methods The expression of STAT‐1 messenger RNA (mRNA)