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Abnormal B-type Ca2+ channel activity contributes to Ca2+-dependent signaling of cardiac myocyte apoptosis

✍ Scribed by Morgana Henaff; Sylvestre Antoine; Jean-Jacques Mercadier; Alain Coulombe; Stéphane N. Hatem


Book ID
117141128
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
136 KB
Volume
33
Category
Article
ISSN
0022-2828

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✍ Christoph Romanin; Jan -Olof Karlsson; Hansgeorg Schindler 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 337 KB

Ca(2+)-induced inactivation of L-type Ca2+ channels is proposed as an important negative feedback mechanism regulating Ca2+ entry. Here, for the first time, evidence for modification of heart L-type Ca2+ channel activity by cytoplasmic calcium is provided from excised inside-out membrane patches. Ba