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Ability of fibrinogen γ-derived dodecapeptides with different sequences to bind to rat platelets

✍ Scribed by Koji Tokutomi; Toshiaki Tagawa; Maki Korenaga; Masatoshi Chiba; Tomohiro Asai; Naohide Watanabe; Shinji Takeoka; Makoto Handa; Yasuo Ikeda; Naoto Oku


Book ID
118454348
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
589 KB
Volume
438
Category
Article
ISSN
0378-5173

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Affinity of fibrinogen binding to platel
✍ Hiroshi Mohri; Takao Okubo 📂 Article 📅 1996 🏛 Springer US 🌐 English ⚖ 534 KB

Arg-Gly-Asp (RGD)-containing peptides and the peptide unique to fibrinogen in the C-terminal domain of the gamma chain are important for fibrinogen binding to platelet membrane glycoprotein (GP) II b/III a. We synthesized a unique hybrid peptide of YRGDSPLGGAKQAGDV encompassing the RGD sequence (RGD