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ABI 007 shows antitumour activity in taxane-resistant breast cancer

Book ID
120859363
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2003
Weight
134 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## Abstract Constitutive bcl‐2 overexpression increases the tumorigenic and metastatic potential of doxorubicin‐resistant, estrogen‐independent, MCF‐7 ADR human breast cancer cells. We evaluated the sensitivity to taxanes (paclitaxel, docetaxel and IDN 5109) of 2 bcl‐2‐overexpressing MCF‐7 ADR clon