Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers
โ Scribed by Luoping Zhang; Nathaniel Rothman; Guilan Li; Weihong Guo; Wei Yang; Alan E. Hubbard; Richard B. Hayes; Songnian Yin; Wei Lu; Martyn T. Smith
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 176 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20306
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract We compared genomic breakpoints at the __PML__ and __RARA__ loci in 23 patients with therapyโrelated acute promyelocytic leukemia (tโAPL) and 25 de novo APL cases.Eighteen of 23 tโAPL cases received the topoisomerase II poison mitoxantrone for their primary disorder. DNA breaks were clu
## Abstract Multicolor fluorescence in situ hybridization (MโFISH) was performed on bone marrow cells of 116 unselected cases of therapyโrelated myelodysplasia (tโMDS) or acute myeloid leukemia (tโAML), and the results were compared with those of previously performed with Gโbanding. Among 18 patien