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Aberrant promoter methylation of Dab2 gene in myelodysplastic syndrome

✍ Scribed by Yang, Yujuan; Zhang, Qingxia; Xu, Feng; Chang, Chunkang; Li, Xiao

Book ID
119828186
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
224 KB
Volume
89
Category
Article
ISSN
0902-4441

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## Background: Aberrant methylation of gene promoter region is responsible for inappropriate gene silencing, and it has been associated to initiation and progression of cancer. aberrant promoter methylation is frequently observed in adult patients with myelodysplastic syndrome (mds), but in pediatr