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Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line

โœ Scribed by Kim, Wan-ju; Vo, Quynh N; Shrivastav, Meena; Lataxes, Tamara A; Brown, Kevin D


Book ID
110066676
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
343 KB
Volume
21
Category
Article
ISSN
0950-9232

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Aberrant splicing of the ATM gene associ
โœ Yosuke Ejima; Lichun Yang; Masao S. Sasaki ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 181 KB ๐Ÿ‘ 2 views

Inherited mutations of the ATM gene are responsible for the human autosomal recessive disorder ataxia-telangiectasia (A-T) characterized by pleiotropic clinical manifestations. ATM mutations are also involved in the development of sporadic human cancers such as T-cell prolymphocytic leukemia and B-c