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Aberrant Gene Methylation in the Neoplastic Progression of Barrett's Esophagus: Identification of Candidate Diagnostic Markers

✍ Scribed by Dennis J. Yang Wu; Tracy C. Yab; William R. Taylor; Douglas W. Mahoney; John B. Kisiel; Mary E. Devens; Julie A. Simonson; Yvonne Romero; David A. Ahlquist

Book ID
119432745
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
388 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Hypermethylation of secreted frizzled‐related proteins (__SFRP__) genes frequently occurs with several cancers but has not been studied in esophageal adenocarcinoma or its precursorβ€”Barrett's esophagus. To explore the role of __SFRP__ methylation in the neoplastic progression of Barrett