𝔖 Bobbio Scriptorium
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Aberrant expression of TopBP1 in breast cancer

✍ Scribed by J J Going; C Nixon; E S Dornan; W Boner; M M Donaldson; I M Morgan

Book ID
108780286
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
852 KB
Volume
50
Category
Article
ISSN
0309-0167

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## Abstract Mutations in tumor‐suppressor gene __BARD1__ have been found in inherited and spontaneous breast, ovarian and uterine cancers. __BARD1__ plays a critical role in DNA repair and ubiquitination as binding partner of __BRCA1,__ with which it colocalizes to nuclear dots. Independently of __

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