Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia
โ Scribed by Nakayama, T; Hieshima, K; Arao, T; Jin, Z; Nagakubo, D; Shirakawa, A-K; Yamada, Y; Fujii, M; Oiso, N; Kawada, A
- Book ID
- 110072965
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 582 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Experiments were undertaken to investigate a genetic event involved in leukemogenesis in adult Tโcell leukemia (ATL). For this purpose, the __p53__ gene was chosen for study, since alteration of the gene has been found in a wide variety of human cancers. Structures and expression of the