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Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines

✍ Scribed by Xiang-wu Ding; He-sheng Luo; Xiong Jin; Juan-juan Yan; Yao-wei Ai

Book ID
107576593
Publisher
Springer US
Year
2007
Tongue
English
Weight
251 KB
Volume
24
Category
Article
ISSN
1357-0560

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Gastrointestinal carcinomas synthesize elevated levels of prostaglandin E(2) (PGE(2)), which has been mechanistically linked to carcinogenesis. Recently, microsomal prostaglandin E synthase-1 (mPGES-1) was cloned, which seems to be inducible and linked to cyclooxygenase-2 (Cox-2) in the biosynthesis