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Aberrant copy numbers of ALK gene is a frequent genetic alteration in neuroblastomas

✍ Scribed by Manish Mani Subramaniam; Marta Piqueras; Samuel Navarro; Rosa Noguera


Book ID
116534746
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
128 KB
Volume
40
Category
Article
ISSN
1532-8392

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## Abstract The tightly controlled network of cell cycle genes consists of a core of cyclin dependent kinases (CDKs) that are activated by periodically expressed cyclins. The activity of the cyclin‐CDK complexes is regulated by cyclin dependent kinase inhibitors (CDKIs) and multiple signal transduc