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ABCG2/V-ATPase was associated with the drug resistance and tumor metastasis of esophageal squamous cancer cells

✍ Scribed by Huang, Lijun; Lu, Qiang; Han, Yong; Li, Zhe; Zhang, Zhipei; Li, Xiaofei


Book ID
119910122
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
317 KB
Volume
7
Category
Article
ISSN
1746-1596

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## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) Ξ±, Ξ², and Ξ³ chains. The Ξ² and Ξ³ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2RΞ± lacks