ABC Transporters, Drug Resistance, and Cancer Stem Cells
β Scribed by Michael Dean
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 216 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1083-3021
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ATP-binding cassette (ABC) transporters are members of a protein superfamily which can be responsible for efflux of drugs from cells of target organisms. In this way, the transporters may provide a mechanism of protection against cytotoxic drugs. In laboratory-generated mutants of fungi, overproduct
## Abstract Since the discovery of antibiotic therapeutics, the battles between humans and infectious diseases have never been stopped. Humans always face the appearance of a new bacterial drugβresistant strain followed by new antibiotic development. However, as the genome sequences of infectious b