Abbreviated nomenclature of synthetic polypeptides (polymerized amino acids): Revised recommendations (1971)

• Publisher: Wiley (John Wiley & Sons)
• Year: 1972
• Tongue: English
• Weight: 375 KB
• Volume: 11
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.1972.360110202

✦ Synopsis

Abbreviated Nomenclature of Synthetic

Polypeptides (Polymerized Amino Acids) *:

Revised Recommendations (1971)""

IUPAC-IUB COi\lMISSION ON BIOCHEAIICAL NOMENCLATURE

The numerous studies on the physical, chemical, and biological propertics of synthetic polypeptides have brought with them different ways of describing, in abbreviated form, these products, whose structures are often incompletely known. The use of a variety of nomenclatures complicates the literature; hence, a consistent and clearly defined system for naming such polypeptides is desirable. The proposals set forth here, which represent the consensus of many discussions and suggestions, should aid in systematizing the nomenclature of a wide variety of synthetic polypeptides.

These proposals are based on large part on the abbreviated nomenclature devised by Gill2 and by Sela and 0the1-s.~ They utilize the symbols and conventions set forth in Section 2 of "Revised Tentative Rules for Abbreviations and Symbols of Chemical Names of Special Interest in Biological Chemistry" * and in "Abbreviated Designation of Amino Acid Derivatives and Peptides," and they add only those terms or conventions needed for the specification of polymers but not encompassed by these schemes.

* Document of the IUPAC-IUB Commission on Biochemical Nomenclature (CBN), originally approved arid published by IUPAC and IUB in October 1967,l and again, in the present revised form, in 1971, approved and published by permission of the International Union of Pure and Applied Chemistry and the International Union of Biochemistry. Comments on these Recommendations may be sent to any member of CBN: 0. Hoffmann-Ostenhof (Chairman), W.