Monocyclic β-lactam antibiotics
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Christopher M. Cimarusti; Richard B. Sykes
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Article
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1984
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John Wiley and Sons
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English
⚖ 958 KB
reevaluation of beta-lactam bond deformation as a criterion for a penicillin-like mode-of-action. ## 11. MECHANISM OF ACTION The mechanism of action of the naturally-occurring monobactams was examined at an early They were shown to interact with certain of the penicillin-binding proteins (PBP's) o