Ab initio study of catalyzed and uncatalyzed amide bond formation as a model for peptide bond formation: Ammonia-formic acid and ammonia-glycine reactions

Ab initio study of catalyzed and uncatal

Ab initio study of catalyzed and uncatalyzed amide bond formation as a model for peptide bond formation: Ammonia-Glycine reactions

✍ Tetsuro Oie; Gilda H. Loew; Stanley K. Burt; Robert D. Macelroy 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 1006 KB

As a model reaction for peptide and bond formation, the s N 2 reactions between glycine and ammonia have been studied with and without amine catalysis: using ab initio molecular-orbital methods. For each of the catalyzed and uncatalyzed reactions, two reaction mechanisms have been examined: a two-s