𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain

✍ Scribed by Takanori Harada; Kenji Yamagishi; Tatsuya Nakano; Kazuo Kitaura; Hiroaki Tokiwa


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
209 KB
Volume
377
Category
Article
ISSN
0028-1298

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Ab initio quantum mechanical study of th
✍ Kaori Fukuzawa; Kazuo Kitaura; Masami Uebayasi; Kotoko Nakata; Tsuguchika Kaminu 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 623 KB

## Abstract We have theoretically examined the relative binding affinities (RBA) of typical ligands, 17β‐estradiol (EST), 17α‐estradiol (ESTA), genistein (GEN), raloxifene (RAL), 4‐hydroxytamoxifen (OHT), tamoxifen (TAM), clomifene (CLO), 4‐hydroxyclomifene (OHC), diethylstilbestrol (DES), bispheno

A method for characterization of endogen
✍ Carol D. Banner; Annika Goos-Nilsson; Jan Sjövall; Jan-Åke Gustafsson; Joseph J. 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 919 KB

An analytical method is described whereby progesterone is isolated from pregnancy plasma on the basis of the high affinity and specificity of the progesterone receptor for its ligand. Partially purified progesterone receptor ligand-binding domain, expressed as a protein A fusion protein in Escherich

CH/π hydrogen bonds determine the select
✍ Tomonaga Ozawa; Kosuke Okazaki 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 320 KB

## Abstract The CH/π hydrogen bond is a weak molecular force occurring between CH groups (soft acids) and π‐systems (soft bases), and has been recognized to be important in the interaction of proteins with their specific ligands. For instance, it is well known that Src homology‐2 protein (SH2) reco

Theoretical studies on opioid receptors
✍ Hua Liang Jiang; Xiao Qin Huang; Suo Bao Rong; Xiao Min Luo; Jian Zhong Chen; Yu 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 2 views

Based on our previous result of the three-dimensional model of the µ-opioid receptor, binding conformations of 13 fentanyl analogs and three-dimensional structures for the complexs of these analogs with µ-opioid receptor were constructed employing the molecular modeling method and our binding confor