The role of helix formation in the foldi
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Sosnick, Tobin R.; Jackson, Sharon; Wilk, Rosemarie R.; Englander, S. Walter; De
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Article
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1996
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John Wiley and Sons
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English
⚖ 652 KB
To determine when secondary structure forms as two chains coalesce to form an alpha-helical dimer, the folding rates of variants of the coiled coil region of GCN4 were compared. Residues at non-perturbing positions along the exterior length of the helices were substituted one at a time with alanine