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Ab initio folding of extended α-helix: A theoretical study about the role of electrostatic polarization in the folding of helical structures

✍ Scribed by Lazim, Raudah; Wei, Caiyi; Sun, Tiedong; Zhang, Dawei


Book ID
121200969
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
791 KB
Volume
81
Category
Article
ISSN
0887-3585

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To determine when secondary structure forms as two chains coalesce to form an alpha-helical dimer, the folding rates of variants of the coiled coil region of GCN4 were compared. Residues at non-perturbing positions along the exterior length of the helices were substituted one at a time with alanine