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AAV5-mediated gene transfer to the parotid glands of non-human primates

✍ Scribed by Voutetakis, A; Zheng, C; Cotrim, A P; Mineshiba, F; Afione, S; Roescher, N; Swaim, W D; Metzger, M; Eckhaus, M A; Donahue, R E

Book ID: 109855228
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 876 KB
Volume: 17
Category: Article
ISSN: 0969-7128
DOI: 10.1038/gt.2009.123

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## Abstract The CD40‐ligand (CD40L) is a key molecule for the activation of dendritic cells (DCs), followed by the induction of DC maturation and cytokine production. Here we found that DC infected with adenovirus vector encoding human CD40L (CD40L‐DC) displayed significantly higher levels of immun