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AAV vector-mediated suicide gene therapy enhanced by irradiation in HNSCC

โœ Scribed by Takeharu Kanazawa; Hiroaki Mizkami; Takashi Okada; Hiroshi Nishino; Keiya Ozawa; Keiichi Ichimura


Book ID
117399514
Publisher
SAGE Publications
Year
2003
Tongue
English
Weight
44 KB
Volume
129
Category
Article
ISSN
0194-5998

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## Abstract Safety, efficacy and enhanced transgene expression are the primary concerns while using any vector for gene therapy. One of the widely used vectors in clinical trials is adenovirus which provides a safe way to deliver the therapeutic gene. However, adenovirus has poor transduction effic