๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

โœ Scribed by Zacchigna, Serena; Zentilin, Lorena; Morini, Monica; Dell'Eva, Raffaella; Noonan, Douglas M; Albini, Adriana; Giacca, Mauro


Book ID
110019063
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
332 KB
Volume
11
Category
Article
ISSN
0929-1903

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Tissue inhibitor of metalloproteinases-1
โœ Yasuhide Ikenaka; Hitoshi Yoshiji; Shigeki Kuriyama; Junichi Yoshii; Ryuichi Nog ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 224 KB ๐Ÿ‘ 1 views

## Abstract The tissue inhibitor of matrix metalloproteinasesโ€1 (TIMPโ€1) has been recognized as a multifunctional protein. The role of TIMPs in cancer remains the subject of conflicting reports with an antitumor activity or a tumor growth stimulation activity by several mechanisms. The aim of our s

Paradoxical effects of tissue inhibitor
โœ Florence Apparailly; Daniรจle Noรซl; Virginie Millet; Andrew H. Baker; Gina Lisign ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 630 KB

Objective. The imbalance between matrix metalloproteinases (MMPs) 1, 3, and 9 and their specific inhibitor, tissue inhibitor of metalloproteinases 1 (TIMP-1), is a critical step in cartilage injury and angiogenesis in arthritis. To explore the therapeutic potential of TIMP-1 gene transfer in erosive

Efficacy of dendrimer-mediated angiostat
โœ Loรฏc Vincent; Julia Varet; Jean-Yves Pille; Heidi Bompais; Paule Opolon; Andrei ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 785 KB

## Abstract Gene transfer is an attractive approach to fight cancer by targeting cancer cells or their vasculature. Our study reports the inhibition of tumor growth and angiogenesis by a nonviral method using dendrimers associated with 36โ€mer anionic oligomers (ON36) for delivering angiostatin (Kri