[AAPS Advances in the Pharmaceutical Sciences Series] Clinical Trial Simulations Volume 1 || Recent Developments in Physiologically Based Pharmacokinetic Modeling

[AAPS Advances in the Pharmaceutical Sci

[AAPS Advances in the Pharmaceutical Sciences Series] Clinical Trial Simulations Volume 1 || Application of Pharmacokinetic–Pharmacodynamic Modeling and Simulation for Erythropoietic Stimulating Agents

✍ Kimko, Holly H. C.; Peck, Carl C. 📂 Article 📅 2010 🏛 Springer New York 🌐 English ⚖ 282 KB

There have been tremendous advancements in application of modeling and simulation (M&S) in drug development during the last decade. The pharmaceutical companies started to pay more attention to implement simulation exercises in drug development in order to achieve cost effectiveness. The Food and Dr

[AAPS Advances in the Pharmaceutical Sci

[AAPS Advances in the Pharmaceutical Sciences Series] Clinical Trial Simulations Volume 1 || The Application of Drug-Disease Models in the Development of Anti-Hyperglycemic Agents

✍ Kimko, Holly H. C.; Peck, Carl C. 📂 Article 📅 2010 🏛 Springer New York ⚖ 464 KB

[AAPS Advances in the Pharmaceutical Sci

[AAPS Advances in the Pharmaceutical Sciences Series] Pediatric Formulations Volume 11 || Pediatric Development: Physiology. Enzymes, Drug Metabolism, Pharmacokinetics and Pharmacodynamics

✍ Bar-Shalom, Daniel; Rose, Klaus 📂 Article 📅 2014 🏛 Springer New York 🌐 English ⚖ 377 KB

Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first chang

[AAPS Advances in the Pharmaceutical Sci

[AAPS Advances in the Pharmaceutical Sciences Series] Clinical Trial Simulations Volume 1 || Balancing Efficacy and Safety in the Clinical Development of an Atypical Antipsychotic, Paliperidone Extended-Release

✍ Kimko, Holly H. C.; Peck, Carl C. 📂 Article 📅 2010 🏛 Springer New York 🌐 English ⚖ 426 KB

There have been tremendous advancements in application of modeling and simulation (M&S) in drug development during the last decade. The pharmaceutical companies started to pay more attention to implement simulation exercises in drug development in order to achieve cost effectiveness. The Food and Dr

[AAPS Advances in the Pharmaceutical Sci

[AAPS Advances in the Pharmaceutical Sciences Series] Clinical Trial Simulations Volume 1 || A Model-Based PK/PD Antimicrobial Chemotherapy Drug Development Platform to Simultaneously Combat Infectious Diseases and Drug Resistance

✍ Kimko, Holly H. C.; Peck, Carl C. 📂 Article 📅 2010 🏛 Springer New York ⚖ 639 KB

[AAPS Advances in the Pharmaceutical Sci

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || Non-clinical Safety Studies for the Conduct of Human Clinical Trials for Pharmaceuticals: ICH M3 and M3(R2)

✍ van der Laan, Jan Willem; DeGeorge, Joseph J. 📂 Article 📅 2013 🏛 Springer New York ⚖ 146 KB