A437 Frequent Amplification of IL-6 Receptor Gene in Patients with Multiple Myeloma
β Scribed by Park, HK; Min, HJ; Cho, HI; Yoon, SS; Suh, CW; Lee, JH; Lee, DS
- Book ID
- 118629357
- Publisher
- CIG Media Group, LP.
- Year
- 2009
- Tongue
- English
- Weight
- 84 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1557-9190
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## Background: The effect of interleukin-6 (il-6), the major growth factor for myeloma cells, may be enhanced by soluble il-6 receptor (sil-6r). therefore, the current study investigated the clinical significance of serum sil-6r in patients with multiple myeloma (mm). ## Methods: Serum levels of
## Abstract Antigenic targets of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) paraproteins might play a role in the pathogenesis of these neoplasms. We screened a human fetal brainβderived macroarray with the IgA or IgG containing sera of 192 consecutive MGUS