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A20 attenuates vascular smooth muscle cell proliferation and migration through blocking PI3k/Akt singlingin

โœ Scribed by Ai-Bing Wang; Hong-Liang Li; Ran Zhang; Zhi-Gang She; Hou-Zao Chen; Yue Huang; De-Pei Liu; Chih-Chuan Liang


Book ID
106577055
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
670 KB
Volume
14
Category
Article
ISSN
1021-7770

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## Abstract In our previous study, bradykinin (BK) exerts its mitogenic effect through Ras/Raf/MEK/MAPK pathway in vascular smooth muscle cells (VSMCs). In addition to this pathway, the nonโ€receptor tyrosine kinases (Src), EGF receptor (EGFR), and phosphatidylinositol 3โ€kinase (PI3โ€K) have been imp