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A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene

โœ Scribed by Gen Kobashi; Akira Hata; Kaori Ohta; Hideto Yamada; EmiHirayama Kato; Hisanori Minakami; Seiichiro Fujimoto; Kiyotaro Kondo


Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
182 KB
Volume
49
Category
Article
ISSN
1435-232X

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Association of a variant of the angioten
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The contribution of genetic factors to hypertension in pregnancy, including pre-eclampsia, has been well documented. The association with a common molecular variant of the angiotensinogen (AGT) gene, in which methionine (M235) is substituted for threonine (T235) at residue 235, has been reported in