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A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor

✍ Scribed by Knaut, Holger; Werz, Christian; Geisler, Robert; The Tübingen 2000 Screen Consortium, ; Nüsslein-Volhard, Christiane


Book ID
109890811
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
344 KB
Volume
421
Category
Article
ISSN
0028-0836

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Background and Objectives: Using the technique of differential hybridization of Atlas TM Human cDNA expression arrays, we previously reported the isolation of a G protein coupled receptor, CXCR-4, which is overexpressed in glioblastoma multiforme tumor tissue (GMTT) compared to normal brain tissue (