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A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment

✍ Scribed by Juraj Gregan; Lut Van Laer; Louis D. Lieto; Guy Van Camp; Stephen E. Kearsey


Book ID
117618019
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
854 KB
Volume
1638
Category
Article
ISSN
0925-4439

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## Communicated by Dvorah Abeliovich Autosomal recessive nonsyndromic hearing impairment (NSHI) is a heterogeneous condition, for which 53 genetic loci have been reported, and 29 genes have been identified to date. One of these, OTOF, encodes otoferlin, a membrane-anchored calcium-binding protein t