A Wnt/β-catenin negative feedback loop inhibits interleukin-1–induced matrix metalloproteinase expression in human articular chondrocytes
✍ Scribed by Bin Ma; Clemens A. van Blitterswijk; Marcel Karperien
- Book ID
- 112002719
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 569 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To investigate the effects of prostaglandin D~2~ (PGD~2~) on interleukin‐1β (IL‐1β)–induced matrix metalloproteinase 1 (MMP‐1) and MMP‐13 expression in human chondrocytes and the signaling pathways involved in these effects. ## Methods Chondrocytes were stimulated with I
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