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A Wittig reaction on mucochloric and mucobromic acids. Preparation of ethyl (2E, 4Z -4,5-dihalo-2,4-pentadienoates and alkyl 2E -5-bromo-2-penten-4-ynoates

✍ Scribed by Ali H. Al-Hakim; Alan H. Haines


Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
242 KB
Volume
23
Category
Article
ISSN
0040-4039

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✦ Synopsis


Reaction of mucochloric and mucobromic acid with ( ethoxycarhonylmethylene) triphenylphosphorane affords the ethyl ester of (2E. 43 -4,5_dichloro-and ( 2g, 4a -4,5_dibromo-2,4-penta-


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Telluro-directed regiospecific and highl
✍ Yao-Zeng Huang; Xue-Sheng Mo; Lei Wang πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 228 KB

Ethyl 5-telluro-(2E,4Z)-pentadienoate 2, which is prepared by the Wittig olefination of (Z)-13telluroacrolein 1, reacted very rapidly with organocuprates 3 at -78Β°C to form exclusively the corresponding 5-substituted products 4 with high stereoselectivity and in excellent yields.