A Water-Soluble Calix[4]arene-Based Podand Incorporating 4,4′-Dicarboxy-2,2′-bipyridine Chelating Units − Synthesis and Complexation Properties towards Copper Ions

✍ Scribed by Nicolas Psychogios; Jean-Bernard Regnouf-de-Vains; Helen M. Stoeckli-Evans

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 205 KB
• Volume: 2004
• Category: Article
• ISSN: 1434-1948
• DOI: 10.1002/ejic.200300690

✦ Synopsis

Abstract

A water‐soluble calix[4]arene‐based podand has been prepared by incorporation, at the lower rim, of two 4,4′‐dicarboxy‐2,2′‐bipyridine units in opposite positions. The association between its coordination and hydrophilic properties were beneficial to the complexation and solubilization of copper(I) in water, even in the presence of bovine serum albumin. The ligand and its corresponding Cu^I^ complex have been fully characterized, but attempts to crystallize them have been unsuccessful so far. For this reason, the dinuclear ZnCl~2~ complex of the organic solvent soluble tetraester intermediate has been crystallized, and subjected to X‐ray diffraction analysis, confirming the expected podand‐like structure of the ligand. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)