A very slow ElcB elimination under extreme ElcB conditions

✍ Scribed by Shmaryahu Hoz; Michael Albeck; Zvi Rappoport

• Publisher: Elsevier Science
• Year: 1972
• Tongue: French
• Weight: 250 KB
• Volume: 13
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)94086-9

✦ Synopsis

Most work dealing with EloB eliminations (equation 1, B = base, X end/or Y = eleotron attracting groups, Z = leavin g group)' was under oonditions where k2> k_l[BH+] (eirrwzrsible oasee) or k2<k_l[BHr ("p re-equilibrium oasee) where the osrbanions $are formed in steady-state concentrations. lb Another variant, designated VloB of the eeoond types2 or "irreversible first order oexbsnionic eliminatione,3 where &is formed in en appreoiable ooncentration end k2 is rate determining was recently reoognized. 2-7 The prediction6 that B + R1R2CZ-CHXY' ,& lU?+ + R1R2CZ-&Y