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A Versatile Synthesis of Pyrazolo[3,4-c]isoquinoline Derivatives by Reaction of 4-Aryl-5-aminopyrazoles with Aryl/Heteroaryl Aldehydes: The Effect of the Heterocycle on the Reaction Pathways.

✍ Scribed by Sergei L. Bogza; Konstantin I. Kobrakov; Anna A. Malienko; Igor F. Perepichka; Sergei Yu. Sujkov; Martin R. Bryce; Svetlana B. Lyubchik; Andrei S. Batsanov; Natalya M. Bogdan


Publisher
John Wiley and Sons
Year
2005
Weight
25 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of 2,3-Diaryl-3H-pyrrolo[2,3-c
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## Abstract The reaction of aryl(3‐isocyanopyridin‐4‐yl)methanones **1**, easily prepared from commercially available pyridin‐3‐amine, with aryl __Grignard__ reagents gave, after aqueous workup, 2,3‐diaryl‐3__H__‐pyrrolo[2,3‐__c__]pyridin‐3‐ols **2**. These rather unstable alcohols were __O__‐acyla