A versatile approach to the synthesis of highly functionalised carbocycles
✍ Scribed by Huib Ovaa; Jeroen D.C. Codée; Bas Lastdrager; Herman S. Overkleeft; Gijs A. van der Marel; Jacques H. van Boom
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 220 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
A synthetic route towards conduramine and carbasugar derivatives based on the transformation (i.e. two-carbon Wittig olefination and ester reduction) of the Vesella rearrangement product derived from D-galacto6e followed by either a [3,3] Overman or a [2,3]-Wittig-Still sigmatropic rearrangement, and subsequent ring-closing metathesis, is presented.
📜 SIMILAR VOLUMES
The reaction of (phenyldimethyl)silylmethyl.magnesiu chloride with benzyl 2,3,4tri-0-benzyl-a-D-manno-hexodialdo-1,5-pyranoside affords the corresponding L-glycero-Dmanno-addition product having at C-7 the phenyldim:thylsilyl (PDMSi) group. The latter silanyl compound survived benzylation as veil as
A growing number of alkaloids bearing a close structural relationship to the morphine bases have recently been isolated from various Stephania species of menispermaceous plants. To date six members of this class of hasubanan alkaloids have been characterized (1). ## WC, 3 Cepharamine (I) (Z), th