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A Validated Stable Isotope Dilution Liquid Chromatography Tandem Mass Spectrometry Assay for the Trace Analysis of Cocaine and Its Major Metabolites in Plasma

✍ Scribed by Singh, Gurkeerat; Arora, Vinod; Fenn, P. Thomas; Mets, Berend; Blair, Ian A.


Book ID
120487706
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
79 KB
Volume
71
Category
Article
ISSN
0003-2700

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## Abstract __N__‐acetylaspartic acid (NAA) is a specific urinary marker for Canavan disease, an autosomal recessive leukodystrophy. We developed a β€˜dilute and shoot’ stable isotope dilution liquid chromatography tandem mass spectrometry (LC‐MS/MS) method for determination of NAA in urine. Deuterat