A Useful Route to Optically Active 4-Oxygenated 4,5-Dihydroisoxazoles
β Scribed by Wade, Peter A.; Shah, Sharmila S.; Govindarajan, Lakshmi
- Book ID
- 120578408
- Publisher
- American Chemical Society
- Year
- 1994
- Tongue
- English
- Weight
- 246 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3263
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Optically active (4S,5R)-dihydroisoxazoles 5a -c (90 -91% ee) have been prepared by reaction of the epoxyketones 4a -c with hydroxylamine. Reduction of compounds 5a and 5b using lithium aluminium hydride took place exclusively from the Re face to give (1R,2S,3S)-1,3-disubstituted-3-aminopropane-1,2-