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A Unifying Ontology to Integrate Histological and Clinical Observations for Drug-Induced Liver Injury

✍ Scribed by Wang, Yuping; Lin, Zhi; Liu, Zhichao; Harris, Stephen; Kelly, Reagan; Zhang, Jie; Ge, Weigong; Chen, Minjun; Borlak, Jürgen; Tong, Weida


Book ID
122102130
Publisher
American Society for Investigative Pathology
Year
2013
Tongue
English
Weight
776 KB
Volume
182
Category
Article
ISSN
0002-9440

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Drug-induced liver injury (DILI) is largely a diagnosis of exclusion and is therefore challenging. The US Drug-Induced Liver Injury Network (DILIN) prospective study used two methods to assess DILI causality: a structured expert opinion process and the Roussel-Uclaf Causality Assessment Method (RUCA