A three-dimensional model of the δ-opioi
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Mark D. Shenderovich; Subo Liao; Xinhua Qian; Victor J. Hruby
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Article
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2000
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Wiley (John Wiley & Sons)
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English
⚖ 359 KB
👁 1 views
A comparative molecular modeling study of delta-opioid ligands was performed under the assumption that potent peptide and nonpeptide agonists may have common three-dimensional (3D) arrangement of pharmacophore groups upon binding to the delta-receptor. Low-energy conformations of the agonists 7-spir